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Lydia Mondavi, owner of the grapeseed-based 29 Cosmetics line, will open her first spa, 29, next month at Atlanta’s Mansion on Peachtree, A Rosewood Hotel (rwmansiononpeachtree.com). This spring, French skin-care company Caudalie debuts a vinothérapy spa, which will host winemaker tastings in NYC’s revamped Plaza hotel (theplaza.com).