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This former convent has been turned into an Orient Express hotel in the Incan town of Cuzco; rooms that once housed nuns are now stocked with pisco cocktail–making kits. The staff’s evening uniforms were created by Peruvian fashion designer Fátima Arrieta; the chef hails from Gastón Acurio’s modern Astrid & Gastón restaurant in Lima and cooks with local ingredients like purple prickly pear. Doubles from $788; palacionazarenas.com.