With its steep natural inclines, simply walking around San Francisco is an intense workout in itself. For a hard-core cardio session, the stairs are steep along the city's famously crooked Lombard Street; those who prefer a flat path can walk across the Golden Gate Bridge.
Stay: The boutique Hotel Palomar created the free People in Motion Running Program. Each weekday at 7 a.m., local runners lead group jogs catered to different fitness levels.
Eat: Plum, opened in 2010 by star chef and forager Daniel Patterson in nearby Oakland, emphasizes grains and vegetables in dishes like bourbon barley risotto with celery root, lemon and kale.