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The plateau of La Mancha, south of Madrid, is rapidly becoming a source of some of Spain’s finest value reds. But it’s also the home of Pago del Vicario, where visitors can taste winemaker Susana López Mendiondo’s impressive bottlings—like the juicy Penta ($15), a blend of five red varieties—stay the night in the modernist hotel, and dine on chef José Alfonso Merlo Ureña’s wine-focused cuisine (doubles from $105; 011-34-926-666-027 or pagodelvicario.com).